Peptides for sex & libido
3 peptides · T5 1 · T3 2
Three entries, and they sit as far apart as this register gets. One is an approved prescription medicine, licensed in the United States for low sexual desire in premenopausal women and tested against a dummy injection in more than a thousand of them; the effect is real, it is small, and a published re-analysis argues that participants preferred the placebo. The other two are approved nowhere. One is sold online as a tanning injection, where the erections were found along the way and the entire tanning evidence is three men. The other is a hormone the body already makes, studied almost entirely by a single research group. Everything measured on this page comes from a questionnaire about how a person felt, which is the only instrument there is for this and is not the same kind of number as a blood test.
- Approved medicine
PT-141
Bremelanotide · Vyleesi
TherapeuticApproved for low sexual desire that causes distress, in women who have not been through the menopause.
Two large randomised trials found a real but small gain in desire and a drop in distress, while the number of satisfying sexual encounters did not change.
- Tested in people, but barely
Kisspeptin
Kisspeptin-54 · Kisspeptin-10
Gray marketPromoted for libido, fertility and testosterone, and sold as a compounded injection.
It shifts reproductive hormones within minutes, but the one placebo-controlled course lasting weeks failed to raise testosterone.
- Tested in people, but barely
Melanotan II
Melanotan 2 · Melanotan-2
Gray marketSold online as a tanning injection, and separately as something that produces erections.
Two placebo-controlled studies in 20 men found it produces erections; the tanning evidence is one pilot in three men, and the harms are single case reports.