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PEPTIDE READER

Peptides for bones & joints

4 peptides · T5 1 · T4 1 · T3 2

Four entries and a very wide spread. One is an approved osteoporosis medicine with a registered use. One is a supplement whose studies are small and largely funded by the industry that sells it. The other two are sold on the gray market: one was given to people recovering from a hip fracture and did not help them, and the other has nothing on bone but a marker that moved in rats. Only the first was ever tested to treat a bone disease.

  1. Approved medicine

    Teriparatide (PTH 1-34)

    Forsteo · Forteo

    Approved for osteoporosis to strengthen bone and reduce fractures.

    Large controlled trials show fewer spinal and non-spinal fractures in people at high risk.

    Therapeutic
  2. Still being tested in people

    MK-677 (ibutamoren)

    Ibutamoren · Ibutamoren mesylate

    Promoted for muscle growth, better sleep and slower ageing through higher growth hormone levels.

    Trials raised the hormone every time and changed nothing measurable: no more strength, no better function, no effect on the diseases it was tested against.

    Gray market
  3. Tested in people, but barely

    AOD-9604

    AOD9604 · AOD 9604

    Promoted for fat loss, and increasingly for joints, cartilage and anti-ageing.

    A 502-person trial found no more weight loss than dummy tablets, and the injected form people buy has never been tested in anyone.

    Gray market
  4. Tested in people, but barely

    Collagen peptides (hydrolysed collagen)

    hydrolysed collagen · collagen hydrolysate

    Sold as a supplement for skin, hair, bones and joints.

    Small human trials report some skin and joint changes, but many were funded by the industry selling the products.

    Supplement